Nutrition and Psycho-Neuro-Immunology

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Nutrition and Psycho-Neuro-Immunology…what is that!?

By Fleur Borrelli, Clinical Psycho-Neuro-Immunologist and Nutritional Therapist

Nutrition and Psycho-neuro-immunology

Main benefits

Helps with weight management

Helps with hormonal issues

Helps with mental health – anxiety, depression

Helps with stress management

Helps with immune system conditions

Helps with digestive issues

Helps with overall wellness

What is and how it works

Psycho-neuro-immunology (PNI) is a health science focusing on how the mind, the nervous system and the immune system interact and communicate with each other via a complex series of biochemical and nervous system pathways.  Clinical psychoneuroimmunology (cPNI) is the application of this knowledge in a clinical setting and provides clients with a better understanding of their pathway to health.


cPNI is a cutting-edge scientific therapeutic modality that is based on the latest developments in the fields of psychology, neurology, endocrinology, immunology and epigenetics and underpinned by human evolutionary biology.  Our genes have changed very little since Palaeolithic times, between 10,000 and 50,000 BC. But the changes to our lifestyles particularly over the last 50 years are unprecedented.  It is these changes, especially the over-abundance of simple carbohydrate foods coupled with sedentary behaviours, that cause changes in genetic expression that lead to the 35 or so chronic diseases in our society.


Stress is thought of as a psychological overload, however, there are different forms of stress that act as ‘stressors’ for our body such as poor diet, lack of exercise and mineral deficiency.  In addition, adverse events in childhood and traumas challenge our immune system and activate a ‘flight fight’ nervous system response. Theses stressors may induce electrical signals from the brain that can travel down the peripheral nerves causing the release of a neurotransmitter which can jump to the next organ and affect its function.  These same peripheral nerves can influence white blood cells of the immune system. Chronic systemic low-grade inflammation can be the result and is at the root of most chronic diseases.

Treatment is aimed at supporting the immune system through the following:

·      Food as medicine and the timing of meals in relation to exercise

·      Exercise as medicine – how different types of exercise produce metabolic flexibility

·      Psycho-social techniques such as cognitive behavioural therapy, expressive writing, creative psychotherapy

Deep learning

Clients learn about the interactions between the brain, metabolism and the immune system in a process known as deep learning.  Deep learning empowers the client with knowledge which enables them to take control of their health. The strength of treatment is in the application of the latest insights from various areas of science. A personal approach takes a central role, and all physiological aspects are considered.

If any of this is of interest to you, be sure to get in touch with our Psycho-Neuro-Immunologist and Nutritional Therapist Fleur Borrelli on 07766883522

Leslie Abrahams